WiX
Instyler Setup creates MSI installation packages based on latest WiX technology. WiX is an open source project, lead by Microsoft, to create MSI files with open standard XML documents.

Intuitive
Create msi setups straight-forward without any MSI knowledge. When we designed Instyler Setup we had in mind that most Windows software developers do not know much about MSI SDK, Orca or what MSI tables do. Adding typical stuff (installing files, shortcuts, registry values etc.) is made as intuitive as possible. Adding a custom dialog to ask the user for additional data (text or options) is also made as easy with built-in templates. If you wisth, you can still configure every detail in the dialog editor.

Prerequisites
We added a variety of standard prerequisites to support checking for Windows Version, .NET Framework, Adobe Reader, Flash, Java Runtime, Microsoft Office.

Multi-language
Localizing your setup into any language is available at no extra charge. English and German texts are available for all texts and dialogs. Other language texts can be imported from MSI SDK language files and the WiX localization project.
Dialog editor
A state-of-the-art dialog editor allows manipulating all dialogs easily. Wizards help you creating events and configuring settings and dialog sequencing in your setup.

File changes at one place
All file actions like installing files, creating shortcuts, moving files, etc. are configured in a Windows Explorer-like view. Instyler Setup supports dynamic file lists to add a number of files during compile time dynamically.

Other setup actions
Your setup may not just have files. With Instyler Setup you can add registry values, file types, environment variables and Windows Services to be created or modified in your MSI setup.

See http://www.instyler.com for more details and screenshots of Instyler Setup.